Pediatricians’ Perceptions Toward Do Not Resuscitate: A Survey in Saudi Arabia and Literature Review.
by Kaitlin
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To explore attitudes and perceptions towards pediatricians do-not-Resuscitate (DNR) order on certain regions of the world are not fully explored before.A cross-sectional study was conducted between March 4 and May 30, 2018. The pediatrician from three public hospitals in the city Riyadh were asked to respond to the questionnaire consisting of 22 questions designed to meet the objectives of our research.
result A total of 203 pediatricians (51.2% female) completed the questionnaire, both pediatricians junior (JPs) and senior pediatrician (SPs). The majority (58.9% of JPs and 61.4% of SPs) think the patient has the right to require intensive care, although their terminal illness. Half the participants in both groups think that the DNR is the doctor’s decision. Only 9.3% of JPs and 12.5% of SPs feel comfortable discussing DNR with patients / families.
medical schools are also a source of knowledge about the issues DNR, especially for JPs (40.2% vs 20.8% of JPs of SPs, P = 0.005). Half the participants felt that the DNR is consistent with Islamic beliefs, while 57.9% of JPs vs 41.7% of SPs feel they are protected by law. hospital’s policy is clearly to 48.6% from 66.7% vs JPs of SPs, while clear procedures to 35.5% of JPs vs. 49% of SPs.
Several factors are present that can hinder the implementation of the DNR, as doubts about the legally protected, doubts about the consistency with Islamic sharia, unclear policies and procedures, and a lack of training and orientation on issues DNR. Policies may need to include patients as decision makers.
Pediatricians’ Perceptions Toward Do Not Resuscitate: A Survey in Saudi Arabia and Literature Review.
The characteristics of nonsyndromic and potentially polyps Juvenile polyps syndrome: A retrospective cohort analysis.
Juvenile polyps (JPs) are the most common gastrointestinal polyps were diagnosed in children. There is a lack of evidence to distinguish groups of polyps and presence burden and importance of neoplastic changes.A retrospective chart review of patients, ages birth to 18 years old with nonsyndromic JPs conducted from 2003 to 2017.
Data abstracted included basic demographics, age, clinical presentation, colonoscopy findings, and reports pathology. Slide polyps with neoplasia reviewed by pathologist.A total of 213 subjects underwent 326 procedures and 435 polypectomies. Subjects with a positive family history, positive gene mutation, or many (> 10) polyps removed. The group is defined by the number of polyps (1, 2-4, 5-10).
Repeat colonoscopy polyp recurrence was significantly associated with polyp burden (1 polyps: 1.5% / 19.2% of polyps 2-4 / 5-10 polyps 82.6%: P <0.001). distribution of polyps was significantly different between the different groups to support the distribution of isolated distal polyps. JPs keep focus adenomatous reported in 26 (12%) patients. JPs keep focus adenomatous were significantly more likely to be distributed proximal but the existence of a transformation in the adenomatous polyps do not correlate with the number of polyps or possible recurrence of polyps in the repeat colonoscopy.
JP recurrence positive and significant effect associated with polyp burden. JP harbored adenomatous changes independent of the number of polyps, underlining the possible malignant potential in JPs. In the absence of a consistent genotype or pedigree, the presence of adenomatous transformation in JPs should not be construed as a biomarker for teenagers polyposis.JLP syndrome MPS families whose members belong to function as a scaffold protein that links the motor proteins and their cargo for intracellular transport.
Description: A polyclonal antibody for detection of JIP-1 from Human, Mouse, Rat. This JIP-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the non-phosphorylation site of T103
Description: A polyclonal antibody for detection of JIP-1 from Human, Mouse, Rat. This JIP-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the non-phosphorylation site of T103
Description: A polyclonal antibody for detection of JIP-1 from Human, Mouse, Rat. This JIP-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the non-phosphorylation site of T103
Description: A polyclonal antibody for detection of JIP-1 phospho Thr103) from Human, Mouse, Rat. This JIP-1 phospho Thr103) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the phosphorylation site of T103
Description: A polyclonal antibody for detection of JIP-1 phospho Thr103) from Human, Mouse, Rat. This JIP-1 phospho Thr103) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the phosphorylation site of T103
Description: A polyclonal antibody for detection of JIP-1 phospho Thr103) from Human, Mouse, Rat. This JIP-1 phospho Thr103) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the phosphorylation site of T103
Description: A Rabbit Polyclonal antibody against JIP-1 (phospho Thr103) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA
Description: A Rabbit Polyclonal antibody against JIP-1 (phospho Thr103) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA
Description: A polyclonal antibody for detection of JIP-2 from Human, Mouse, Rat. This JIP-2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human JIP-2 at AA rangle: 550-630
Description: A polyclonal antibody for detection of JIP-2 from Human, Mouse, Rat. This JIP-2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human JIP-2 at AA rangle: 550-630
Description: A polyclonal antibody for detection of JIP-2 from Human, Mouse, Rat. This JIP-2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human JIP-2 at AA rangle: 550-630
Description: A polyclonal antibody for detection of JIP-3 from Human, Mouse. This JIP-3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human JIP-3 at AA range: 590-670
Description: A polyclonal antibody for detection of JIP-3 from Human, Mouse. This JIP-3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human JIP-3 at AA range: 590-670
Description: A polyclonal antibody for detection of JIP-3 from Human, Mouse. This JIP-3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human JIP-3 at AA range: 590-670
Description: Anti-PD-1 IgG antibody is a purified recombinant antibody which recognizes human PD1 antigen. This antibody has been functionally tested in two co-culture assays.
Description: Mouse Monoclonal HLA-G (human) Antibody (MEM-G/1). Validated in IHC, WB and tested in Human.
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Although JLP especially cytoplasm, it accumulates as a focus in the perinuclear region when stimulated by extracellular stimuli. focus formation, which change the shape of the nucleus and nuclear pores concentrate, depending on the activation of p38MAPK and retrograde dynein motor protein complex. Extracellular stimuli lead to the withdrawal of PLK1 to centrosome by the JLP, which leads to the maturation of the centrosome and microtubule formation arrays.
