hereditary colon tumors usually part of different syndromes that require management of both diseases intestinal and extra-intestinal. polyposis syndrome include: Familial adenomatous polyposis, MUTYH associated polyposis, serrated polyposis syndrome, Peutz-Jeghers syndrome, Juvenile polyposis syndrome and syndrome PTEN-hamartomatous. Of all colorectal cancer (CRC), 5% -10% will be caused by hereditary CRC syndrome underlying. Diagnosis and management of polyposis syndromes continues to evolve as new scientific and technological advances are made in relation to identifying the causative gene and increased sophistication of endoscopic therapy for treating polyps.

This, in addition to the data generated from the meticulous recording by registrants polyposis has helped to guide management in what is otherwise a relatively rare condition. These data help guide clinical management of patients and ‘at risk’ families. Diagnosis is either genetic where possible but clinical recognition is key in the absence of the causative gene is identified. In addition, some may overlap syndrome can complicate diagnosis supplementary.

The purpose of the first polyposis management principles to manage and treat the patient presents and then identify ‘at risk’ patients, through screening and predictive genetic testing, to allow therapeutic endoscopic surveillance and guiding surgical prophylaxis. Because of the complexity of the diagnosis and management of patients and their families should be referred to a genetics center or polyposis registry where specific management can occur.

Practical management of polyposis syndromes.
Practical management of polyposis syndromes.

Index disabled children a voice: Translation, transculturalization and validation for Argentine Spanish.

Voice disorders are very common in the pediatric population, with 6% and 23% of all children experience some form of dysphonia [1,2]. Over the years, patients have been diagnosed. There has been increasing awareness and interest in the study of sound changes in children, and most importantly, its impact in their quality of life.

To do this, the instrument is capable of measuring the quality of life in pediatric patients with vocal pathology is required, which can be widely used in the scientific community. The aim of our study was to carry out the translation, and validation transculturalization pVHI (Pediatric Voice Handicap Index) for the study of Argentine Spanish-speakers.A conducted at Hospital de Pediatria Dr. JP Garrahan in Buenos Aires, Argentina.

It included patients aged between 3 and 18 years. The pVHI translated and transculturalized for populations words and validation, the survey was conducted on two groups of patients: one group may be the children against the background of both the surgical laryngeal reconstruction, and dysphonia (n = 35) and being another group of control patients without pathology sound (n = 35). The survey was conducted among the parents or caregivers of children in question.

A significant differences were found between the two groups, both for pVHI overall score and score survey subgroups (p <0.001) with the optimal internal confidence and good Cronbach Alpha for each of subgroups (functional 0.92; organic and emotional 0.87 0.88). Test-retest reliability revealed for “p-value” with no significant differences (p> 0.05) for each of all subgroups (functional 0.68; organic and emotional 0.32 to 0.72) .the validation and transculturalization of the level of disturbance to residents of Argentina pediatric vocal Spain presented an adequate reliability and validity.

JIP-2 Polyclonal Antibody

ES5356-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against JIP-2 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

JIP-2 Polyclonal Antibody

ES5356-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against JIP-2 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

JIP-1 Polyclonal Antibody

ES2659-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against JIP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

JIP-1 Polyclonal Antibody

ES2659-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against JIP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

JIP-1 Polyclonal Antibody

ABP51660-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of JIP-1 from Human, Mouse, Rat. This JIP-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the non-phosphorylation site of T103

JIP-1 Polyclonal Antibody

ABP51660-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of JIP-1 from Human, Mouse, Rat. This JIP-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the non-phosphorylation site of T103

JIP-1 Polyclonal Antibody

ABP51660-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of JIP-1 from Human, Mouse, Rat. This JIP-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the non-phosphorylation site of T103

JIP-2 Polyclonal Antibody

ABP54357-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of JIP-2 from Human, Mouse, Rat. This JIP-2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human JIP-2 at AA rangle: 550-630

JIP-2 Polyclonal Antibody

ABP54357-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of JIP-2 from Human, Mouse, Rat. This JIP-2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human JIP-2 at AA rangle: 550-630

JIP-2 Polyclonal Antibody

ABP54357-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of JIP-2 from Human, Mouse, Rat. This JIP-2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human JIP-2 at AA rangle: 550-630

Anti-JIP-3 antibody

STJ93801 200 µl
EUR 197
Description: Rabbit polyclonal to JIP-3.

JIP-1 Antibody

3664-100
EUR 316

JIP-1 Antibody

3664-30T
EUR 146

JIP 1 antibody

20R-1697 100 ug
EUR 673
Description: Rabbit polyclonal JIP 1 antibody

JIP-1 (phospho Thr103) Polyclonal Antibody

ES8048-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against JIP-1 (phospho Thr103) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

JIP-1 (phospho Thr103) Polyclonal Antibody

ES8048-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against JIP-1 (phospho Thr103) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

JIP-1 (phospho Thr103) Polyclonal Antibody

ABP57049-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of JIP-1 phospho Thr103) from Human, Mouse, Rat. This JIP-1 phospho Thr103) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the phosphorylation site of T103

JIP-1 (phospho Thr103) Polyclonal Antibody

ABP57049-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of JIP-1 phospho Thr103) from Human, Mouse, Rat. This JIP-1 phospho Thr103) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the phosphorylation site of T103

JIP-1 (phospho Thr103) Polyclonal Antibody

ABP57049-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of JIP-1 phospho Thr103) from Human, Mouse, Rat. This JIP-1 phospho Thr103) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human JIP-1 around the phosphorylation site of T103

Anti-JIP-1 Antibody

A05068 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for JIP-1 Antibody (MAPK8IP1) detection.tested for WB in Human, Mouse, Rat.

Anti-JIP-1 antibody

STJ93799 200 µl
EUR 197
Description: Rabbit polyclonal to JIP-1.

Anti-JIP-2 antibody

STJ93800 200 µl
EUR 197
Description: Rabbit polyclonal to JIP-2.

JIP-1(153-163)

E1KP1081 1mgPHYSICAL AND CHEMICAL PROPERTIES
EUR 456

JIP-1 (153-163)

B5130-1 1 mg
EUR 399

JIP-1 Blocking Peptide

3664BP-50
EUR 153

JIP 1 Blocking Peptide

33R-10537 50 ug
EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of JIP 1 antibody, catalog no. 20R-1697

Anti-Phospho-JIP-1 (T103) antibody

STJ90715 200 µl
EUR 197
Description: Rabbit polyclonal to Phospho-JIP-1 (T103).

Rabbit Polyclonal Antibody to Human Topoisomerase IIb

TG2010-3 250 units
EUR 414

Anti-14-3-3 alpha + beta Rabbit Monoclonal Antibody

M02431-3 100ug/vial
EUR 397
Description: Rabbit Monoclonal 14-3-3 alpha + beta Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-VEGF Receptor 3/FLT4 Antibody

A01276-3 100ug/vial
EUR 334

Anti-active Caspase-3 Rabbit Monoclonal Antibody

M00334-3 100ug/vial
EUR 397
Description: Anti-active Caspase-3 Rabbit Monoclonal Antibody tested for IF, IHC, ICC, WB in Human

Anti-Galectin 3/LGALS3 Antibody (monoclonal, 12B12)

M00621-3 100ug/vial
EUR 334

Anti-Glyceraldehyde 3-Phosphate Dehydrogenase [GAPDH] Monoclonal Antibody

M00227-3 100ul
EUR 397
Description: Mouse Monoclonal Glyceraldehyde 3-Phosphate Dehydrogenase [GAPDH] Antibody. Validated in IHC, WB and tested in Equine.

IL-3 Interleukin-3 Human Recombinant Protein, His Tag

PROTP08700-3 Regular: 50ug
EUR 317
Description: Interleukin-3 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 154 amino acids fragment (20-152) and having a total molecular mass of 17.3kDa and fused with a 20 aa N-terminal His tag. ;The IL3 His is purified by proprietary chromatographic techniques.

3-D Life Thioglycerol

T10-3 180 µl
EUR 48

Individual Reaction Mix 3

G065-3 200 reactions
EUR 167

Western Blot Box - 2 7/8 x 1 3/16 x 3/4in.; 7.3 x 3 x 1.9cm

B1200-3 5/pack
EUR 63.77
Description: Western Blot Boxes

TGF-b-3 Transforming Growth Factor-Beta 3 Human Recombinant Protein, Plant

PROTP10600-3 Regular: 5ug
EUR 317
Description: TGFB3 Human Recombinant produced in plant is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 118 amino acids and having a molecular mass of 27.2kDa. ;The TGFB3 is fused to 6xHis tag at N-terminus and purified by standard chromatographic techniques.

3-D-Life SG-PVA

M81-3 3x 170 µl
EUR 148

3-D Life FG-PVA

M82-3 3x 170 µl
EUR 148

3-D Life SG-Dextran

M91-3 3x 170 µl
EUR 157

3-D Life FG-Dextran

M92-3 3x 170 µl
EUR 157

3-D Life PEG-Link

L50-3 3x 200 µl
EUR 94

3-D Life CD-Link

L60-3 3 x 200 µl
EUR 321

3-D Life RGD Peptide

P10-3 3x 1 µmol
EUR 276

Recombinant Human MMP-3 Protein

PROTP08254-3 10ug
EUR 317
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-3 degrades fibronectin, laminin, collagens III, IV, and X, and cartilage proteoglycans. Recombinant human MMP-3 is a 42.8 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (378 amino acids).

pLenti-CARM1 shRNA-3 Plasmid

PVTBAV03691-3 2 ug
EUR 356

pLenti-CTLA4 shRNA-3 Plasmid

PVTBAV05689-3 2 ug
EUR 356

pLenti-FOXM1 shRNA-3 Plasmid

PVTBAV08732-3 2 ug
EUR 356

pLenti-JUN shRNA-3 Plasmid

PVTBAV11741-3 2 ug
EUR 356

pLenti-LHX6 shRNA-3 Plasmid

PVTBAV12881-3 2 ug
EUR 356

pLenti-MAGEA3 shRNA-3 Plasmid

PVTBAV13661-3 2 ug
EUR 356

pLenti-RUNX3 shRNA-3 Plasmid

PVTBAV20583-3 2 ug
EUR 356

pLenti-Slc7a11 shRNA-3 Plasmid

PVTBAV21973-3 2 ug
EUR 356

pLenti-STAT3 shRNA-3 Plasmid

PVTBAV22921-3 2 ug
EUR 356

Dr. P Kit-Solution 3

K2021010-3 50 ml
EUR 133
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

3-D Life Scrambled RGD Peptide

P11-3 3x 1 µmol
EUR 276

Caspase-3 Inhibitor Q-DEVD-OPh

1175-3
EUR 533

FSH (Human Follicle-stimulating hormone) ELISA test

3 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FSH (Human Follicle-stimulating hormone)

Rabbit Complement 3-4 WK (100-mL)

31061-3 100mL
EUR 1102.48

QuantiMir 3'-Universal Primer (10,000 qPCR reactions)

RA420AU-3 10,000 assays
EUR 178

SeraMir 3'-Universal Primer (10,000 qPCR reactions)

RA800P-3 10,000 reactions
EUR 178

Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit

30009-3 1KIT
EUR 809
Description: Minimum order quantity: 1 unit of 1KIT

3-D Life 10x CB-Buffer (pH 5.5)

B10-3 600 µl
EUR 44

3-D Life 10x CB Buffer (pH 7.2)

B20-3 600 µL
EUR 44

PLGF3 Human, Placenta Growth Factor-3 Human Recombinant Protein, sf9

PROTP49763-3 Regular: 25ug
EUR 317
Description: PLGF3 Human Recombinant produced in Spodoptera frugiperda is a glycosylated homodimer containing 2 chains of 203 amino acids (Leu19-Arg221) and having a molecular mass of 58kDa.;The PLGF-3 is purified by proprietary chromatographic techniques.

Anti-Calretinin Antibody

M04255-3 100ul
EUR 397
Description: Rabbit Polyclonal Calretinin Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-CNP Antibody

M01017-3 100ul
EUR 397
Description: Chicken Polyclonal CNP Antibody. Validated in IHC, WB and tested in Equine, Pig.

Anti-GAP43 Antibody

M01868-3 100ul
EUR 397
Description: Rabbit Polyclonal GAP43 Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-Nanog Antibody

A00153-3 100ug/vial
EUR 294

Anti-IL17C Antibody

A00164-3 100ug/vial
EUR 294

Anti-AICDA Antibody

A00267-3 100ug/vial
EUR 294

Anti-ICOS Antibody

A00291-3 100ug/vial
EUR 334

Anti-TLR1 Antibody

A00429-3 100ug/vial
EUR 334

Anti-IGFBP3 Antibody

A00435-3 100ug/vial
EUR 294

Anti-TANK Antibody

A00445-3 100ug/vial
EUR 334

Anti-FGF23 Antibody

A00478-3 100ug/vial
EUR 294

Anti-Leptin Antibody

A00479-3 100ug/vial
EUR 294

Anti-CD5 Antibody

A00480-3 100ug/vial
EUR 334

Anti-SYK Antibody

A00490-3 100ug/vial
EUR 294

Anti-PON1 Antibody

A00516-3 100ug/vial
EUR 334

Anti-CSF1 Antibody

A00620-3 100ug/vial
EUR 294

Anti-LBP Antibody

A00809-3 100ug/vial
EUR 294

Anti-IL22 Antibody

A00963-3 100ug/vial
EUR 294

Anti-MBL2 Antibody

A01000-3 100ug/vial
EUR 294

Anti-KCNH1 Antibody

A01036-3 100ug/vial
EUR 294

Anti-IL12B Antibody

A01152-3 100ug/vial
EUR 334

Anti-PRMT1 Antibody

A01417-3 100ug/vial
EUR 294

Anti-TFF3 Antibody

A01738-3 100ug/vial
EUR 334

Anti-EIF4A1 Antibody

A03922-3 100ug/vial
EUR 334

Anti-SLIT1 Antibody

A04113-3 100ug/vial
EUR 294

Anti-SORBS1 Antibody

A04426-3 100ug/vial
EUR 334

The rate of decline of vocal child is identified through this simple and practical survey, offer additional information about the child vowel perception by the part of the caregiver. We recommend this survey are included as a valuable tool in the evaluation of dysphonia Spanish-speaking children in the family.